Research in Biophysics is mainly focused on elucidation and characterization of the mechanisms of photodynamic therapy, development of a prospective treatment for several oncological diseases in
vivo on both molecular and cellular levels. On the molecular level, physical and chemical properties of low-density lipoprotein-based delivery systems loaded with photoactive drugs and photosensitizers
are investigated. On the cellular level, research is aimed at monitoring development, and progression of the programmed cell death –apoptosis - as a result of targeted photodynamic action and other
processes. Computational biophysics concentrates on the construction of quantitative predictive models of main mechanisms of molecular events leading to the apoptosis and application of evolutionary
optimization framework to study carcinogenesis. An additional research area is focused on the detection of trace amounts of chemical compounds in solutions, as well as the study of the interactions
of bio-macromolecules with drugs by means of surface-enhanced Raman spectroscopy.
Research in Condensed Matter Physics is focused on the study of the correlations between structural, magnetic and galvanomagnetic properties of amorphous, polycrystalline, and nanocrystalline
materials prepared by rapid quenching in the form of ribbons, powders, wires and thin films.
Research in the Physics of Very Low Temperature is focused on the complex investigation of the ground state of the low-dimensional magnetic systems, geometrically frustrated magnets, and strongly
correlated electron systems. New research activities in the area of nanophysics and nanoelectronics are being planned.
The research in Nuclear and Subnuclear Physics is concentrated on the study of ultrarelativistic heavy ion collisions and on the search for correlations and spin effects in few nucleon systems at
medium energies. The aim is to study the structure of matter at small distances (quark level), the characteristic features of nuclear forces, reaction mechanisms, demonstrations of nuclear spin
structure and polarization effects. Cosmic ray studies, in collaboration with the IEP SAS, are mainly oriented toward cosmic ray components and space weather. Applied nuclear physics deals with
the application of nuclear radiation in medicine. As far as the high energy physics is concerned, one would like to stress the cooperation and membership in two excellent international research
centres: JINR, Dubna, Russia and CERN, Geneve, Switzerland. This collaboration allows us to join the most topical experiments where all the equipments (accelerators and detectors) are maintained
and operated and the data are collected. The home institute concentrates onto data processing and analyses and simulations of experiments on PC clusters and GRID.
Research in the field of Theoretical Physics is focused on diverse modern problems of statistical physics and condensed matter theory, such as investigation of phase transitions and critical phenomena,
theoretical description of magnetic and elastic properties of crystalline and disordered materials, transport properties in giant-magnetoresistive heterostructures, magnetic and electronic properties
of low-dimensional structures, and molecular-based magnetic materials.
Research in Astrophysics concentrates on the study of physical processes in interacting variable stars (symbiotic and cataclysmic variables, contact and near contact binaries), mainly mechanisms
related to the mass transfer between the components of these binaries, which produced the observed activity of these objects.
Research in the field of Physics Teaching is related to the testing and developing new interactive methods and teaching strategies implementing PC based experiments, personal response systems,
and ICT (information and communication technologies) in elementary and secondary school practice and in pre-service and in-service teacher training. Another important research activity is
focused on the study of new approaches in teaching modern physics at the introductory college level, particularly in quantum mechanics and general relativity.